Amy Berger, MD, PhD

Attending Physician

I am a physician-scientist who enjoys working at the intersection of multiple areas of medicine and science. I am interested in physician-scientist training, the application of pathophysiology to clinical reasoning, and the translation of cutting edge technologies to the clinic.
Education
Fellowship, 2017 - Academic Hospital Medicine, University of California, San Francisco
Fellowship, 2017 - Clinical and Translational Science, University of California, San Francisco
Residency, 2016 - Internal Medicine, University of California, San Francisco
MD, PhD, 2012 - PhD in Neuroscience, University of California, San Francisco
BS, 2002 - Biological Sciences, Stanford University
Publications

  1. Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V. Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy. Neurology. Genetics 2024. PMID: 38586598


  2. Hsiao-Nakamoto J, Chiu CL, VandeVrede L, Ravi R, Vandenberg B, De Groot J, Tsogtbaatar B, Fang M, Auger P, Gould NS, Marchioni F, Powers CA, Davis SS, Suh JH, Alkabsh J, Heuer HW, Lago AL, Scearce-Levie K, Seeley WW, Boeve BF, Rosen HJ, Berger A, Tsai R, Di Paolo G, Boxer AL, Bhalla A, Huang F, ALLFTD Consortium. Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia. bioRxiv : the preprint server for biology 2024. PMID: 38405775


  3. Leng K, Cadwell CR, Patrick Devine W, Tihan T, Qi Z, Singhal N, Glenn O, Kamiya S, Wiita A, Berger A, Shieh JT, Titus EW, Paredes MF, Upadhyay V. Cell type specificity of mosaic chromosome 1q gain resolved by snRNA-seq in a case of epilepsy with hyaline protoplasmic astrocytopathy. bioRxiv : the preprint server for biology 2024. PMID: 38328093


  4. Rolfes M, Harroud A, Zorn KC, Tubati A, Omura C, Kurtz K, Matloubian M, Berger A, Chiu CY, Wilson MR, Ramachandran PS. Complement Factor I Gene Variant as a Treatable Cause of Recurrent Aseptic Neutrophilic Meningitis: A Case Report. Neurology(R) neuroimmunology & neuroinflammation 2023. PMID: 37339889


  5. Berger AC, Simchoni N, Auerbach A, Brode WM, Kuperman E, Raffel K, Kubey A, HOMERuN COVID-19 Collaborative Group. Implementation of Clinical Practice Guidelines for Hospitalized Patients With COVID-19 in Academic Medical Centers. "Are Telehealth Visits Feasible for Vulnerable Patients?" 2022. PMID: 35377428


  6. Gu W, Deng X, Lee M, Sucu YD, Arevalo S, Stryke D, Federman S, Gopez A, Reyes K, Zorn K, Sample H, Yu G, Ishpuniani G, Briggs B, Chow ED, Berger A, Wilson MR, Wang C, Hsu E, Miller S, DeRisi JL, Chiu CY. Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids. "Are Telehealth Visits Feasible for Vulnerable Patients?" 2020. PMID: 33169017


  7. Song E, Pincus L, Berger A, Butrymowicz A, Haemel A.. Rosai-Dorfman as a clinical mimicker of relapsing polychondritis Journal of the American Academy of Dermatology Case Reports 2020. PMID:


  8. Berger A, Matloubian M, Shah NP, Wachter RM, DeRisi JL, Anderson M. The Molecular Medicine Investigation Unit: Linking Patient Care and Scientific Inquiry in Physician-Scientist Training. Journal of graduate medical education 2020. PMID: 32089799


  9. Moore PC, Cortez JT, Chamberlain CE, Alba D, Berger AC, Quandt Z, Chan A, Cheng MH, Bautista JL, Peng J, German MS, Anderson MS, Oakes SA. Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma. The Journal of clinical investigation 2019. PMID: 31369399


  10. Wilson MR, Sample HA, Zorn KC, Arevalo S, Yu G, Neuhaus J, Federman S, Stryke D, Briggs B, Langelier C, Berger A, Douglas V, Josephson SA, Chow FC, Fulton BD, DeRisi JL, Gelfand JM, Naccache SN, Bender J, Dien Bard J, Murkey J, Carlson M, Vespa PM, Vijayan T, Allyn PR, Campeau S, Humphries RM, Klausner JD, Ganzon CD, Memar F, Ocampo NA, Zimmermann LL, Cohen SH, Polage CR, DeBiasi RL, Haller B, Dallas R, Maron G, Hayden R, Messacar K, Dominguez SR, Miller S, Chiu CY. Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis. The New England journal of medicine 2019. PMID: 31189036


  11. Berger AC, Whistler JL. Morphine-induced mu opioid receptor trafficking enhances reward yet prevents compulsive drug use. EMBO molecular medicine 2011. PMID: 21656686


  12. Berger AC, Whistler JL. How to design an opioid drug that causes reduced tolerance and dependence. Annals of neurology 2010. PMID: 20437553


  13. Kim JA, Bartlett S, He L, Nielsen CK, Chang AM, Kharazia V, Waldhoer M, Ou CJ, Taylor S, Ferwerda M, Cado D, Whistler JL. Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence. Current biology : CB 2008. PMID: 18207746